Researches of variability of number of copies of fragments of DNA according to a high-performance sekvenirovaniye

It is traditional for detection of chromosomal anomalies apply cytogenetic and molecular and cytogenetic methods. With development technologies sekvenirovaniye became available the new approaches, allowing to identify structural variations from 50 in size pn. Staff of Laboratory of molecular oncology of IBKH RAN together with colleagues from FEDERAL STATE-FINANCED INSTITUTION FMBA FNKTS FHM RUSSIA developed approach for formation of a validation set at level ekzonov and estimated efficiency of the algorithms intended for data of a polnoekzomny sekvenirovaniye. Grigorov A.S. Gordeeva V, Sharova E, Babalyan K, Sultanov R, Govorun...