Deficiency of B12 vitamin caused skin darkening in the black Trinidadian

Physicians from Trinidad and Tobago described excess darkening of skin at the black man. At the patient melanin synthesis because of B12 - scarce anemia amplified, and because of it coloring of feet and palms changed. Doctors made it the diagnosis of pernitsiozny anemia which is most often accompanied by fatigue, short wind and dizziness. Skin darkening, especially in lack of other symptoms, at it meets seldom. The case is described in The New England Jornal of Medicine. Anemia arises because of decrease in the content of hemoglobin in erythrocytes and is usually shown by symptoms of a hypoxia of fabrics: weakness, fast...